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Antiapoptotic Role for Lifeguard in T Cell Mediated Immune Response

Anti-apoptotic protein Lifeguard (LFG) is upregulated on T cells upon in vitro activation. To investigate its role in T cell immunity we infected wild type and LFG knockout bone marrow chimaeras mice with LCMV. We observed a decreased number of LFG KO activated CD8 and CD4 T cells throughout the inf...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Hurtado de Mendoza, Tatiana, Liu, Fei, Verma, Inder M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643990/
https://ncbi.nlm.nih.gov/pubmed/26565411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142161
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