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Bringing Down Cancer Aircraft: Searching for Essential Hypomutated Proteins in Skin Melanoma
We propose an approach to detection of essential genes/proteins required for cancer cell survival. A gene is considered essential if a mutation with high impact upon the function of encoded protein causes death of the cancer cell. We draw an analogy between essential cancer proteins and well-known A...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4643971/ https://ncbi.nlm.nih.gov/pubmed/26565620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142819 |
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