Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection

BST-2 (tetherin, CD317, HM1.24) restricts virus growth by tethering enveloped viruses to the cell surface. The role of BST-2 during influenza A virus infection (IAV) is controversial. Here, we assessed the capacity of endogenous BST-2 to restrict IAV in primary murine cells. IAV infection increased...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Londrigan, Sarah L., Tate, Michelle D., Job, Emma R., Moffat, Jessica M., Wakim, Linda M., Gonelli, Christopher A., Purcell, Damien F. J., Brooks, Andrew G., Villadangos, Jose A., Reading, Patrick C., Mintern, Justine D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643895/
https://ncbi.nlm.nih.gov/pubmed/26566124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142925
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