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The Association between Clinical Response to Ustekinumab and Immunogenicity to Ustekinumab and Prior Adalimumab

BACKGROUND: Immunogenicity due to antidrug antibodies (ADA) to tumor necrosis factor (TNF)-α antagonists is known to decrease treatment response. However, few studies have investigated ADA in ustekinumab, an interleukin-12 and -23 antagonist, in a clinical setting. This study aimed to investigate th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chiu, Hsien-Yi, Chu, Thomas Waitao, Cheng, Yu-Pin, Tsai, Tsen-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643875/
https://ncbi.nlm.nih.gov/pubmed/26566272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142930
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