Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington’s disease

Aberrant glutathione or Ca(2+) homeostasis due to oxidative stress is associated with the pathogenesis of neurodegenerative disorders. The Ca(2+)-permeable transient receptor potential cation (TRPC) channel is predominantly expressed in the brain, which is sensitive to oxidative stress. However, the...

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Bibliografiske detaljer
Udgivet i:Brain
Main Authors: Hong, Chansik, Seo, Hyemyung, Kwak, Misun, Jeon, Jeha, Jang, Jihoon, Jeong, Eui Man, Myeong, Jongyun, Hwang, Yu Jin, Ha, Kotdaji, Kang, Min Jueng, Lee, Kyu Pil, Yi, Eugene C., Kim, In-Gyu, Jeon, Ju-Hong, Ryu, Hoon, So, Insuk
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643628/
https://ncbi.nlm.nih.gov/pubmed/26133660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv188
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