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A phase I study of dasatinib and weekly paclitaxel for metastatic breast cancer
Background: SRC plays an important role in the pathogenesis of metastatic breast cancer (MBC). In preclinical models, paclitaxel and the oral SRC inhibitor dasatinib showed greater antitumor activity than either agent. To determine the maximum tolerated dose of this combination, we conducted a phase...
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Publicado no: | Ann Oncol |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4643618/ https://ncbi.nlm.nih.gov/pubmed/21406471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdr018 |
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