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Age-Associated Increase in Cytokine Production During Systemic Inflammation—II: The Role of IL-1β in Age-Dependent IL-6 Upregulation in Adipose Tissue

Expression of interleukin-6 (IL-6) upon acute inflammatory stress is significantly augmented by aging in adipose tissue, a major source of this cytokine. In the present study, we examined the mechanism of age-dependent IL-6 overproduction using visceral white adipose tissue from C57BL/6 mice. Upon t...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Starr, Marlene E., Saito, Mizuki, Evers, B. Mark, Saito, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643612/
https://ncbi.nlm.nih.gov/pubmed/25344820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu197
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