Crystal structure of an antigenic outer-membrane protein from Salmonella Typhi suggests a potential antigenic loop and an efflux mechanism

ST50, an outer-membrane component of the multi-drug efflux system from Salmonella enterica serovar Typhi, is an obligatory diagnostic antigen for typhoid fever. ST50 is an excellent and unique diagnostic antigen with 95% specificity and 90% sensitivity and is used in the commercial diagnosis test ki...

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Vydáno v:Sci Rep
Hlavní autoři: Guan, Hong-Hsiang, Yoshimura, Masato, Chuankhayan, Phimonphan, Lin, Chien-Chih, Chen, Nai-Chi, Yang, Ming-Chi, Ismail, Asma, Fun, Hoong-Kun, Chen, Chun-Jung
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643347/
https://ncbi.nlm.nih.gov/pubmed/26563565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16441
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