Magnesium homeostasis in colon carcinoma LoVo cells sensitive or resistant to doxorubicin

Neoplastic cells accumulate magnesium, an event which provides selective advantages and is frequently associated with TRPM7overexpression. Little is known about magnesium homeostasis in drug-resistant cancer cells. Therefore, we used the colon cancer LoVo cell model and compared doxorubicin-resistan...

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Udgivet i:Sci Rep
Main Authors: Castiglioni, Sara, Cazzaniga, Alessandra, Trapani, Valentina, Cappadone, Concettina, Farruggia, Giovanna, Merolle, Lucia, Wolf, Federica I., Iotti, Stefano, Maier, Jeanette A M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643312/
https://ncbi.nlm.nih.gov/pubmed/26563869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16538
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