Hemagglutinin Spatial Distribution Shifts in Response to Cholesterol in the Influenza Viral Envelope

Influenza virus delivers its genome to the host cytoplasm via a process of membrane fusion mediated by the viral hemagglutinin protein. Optimal fusion likely requires multiple hemagglutinin trimers, so the spatial distribution of hemagglutinin on the viral envelope may influence fusion mechanism. We...

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Foilsithe in:Biophys J
Main Authors: Domanska, Marta K., Dunning, Rebecca A., Dryden, Kelly A., Zawada, Katarzyna E., Yeager, Mark, Kasson, Peter M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2015
Ábhair:
Membranes
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643271/
https://ncbi.nlm.nih.gov/pubmed/26536268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.09.014
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