Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line

Retinal ganglion cell (RGC) injury and cell death from glaucoma and other forms of optic nerve disease is a major cause of irreversible vision loss and blindness. Human pluripotent stem cell (hPSC)-derived RGCs could provide a source of cells for the development of novel therapeutic molecules as wel...

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Publicado no:Sci Rep
Main Authors: Sluch, Valentin M., Davis, Chung-ha O., Ranganathan, Vinod, Kerr, Justin M., Krick, Kellin, Martin, Russ, Berlinicke, Cynthia A., Marsh-Armstrong, Nicholas, Diamond, Jeffrey S., Mao, Hai-Quan, Zack, Donald J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643248/
https://ncbi.nlm.nih.gov/pubmed/26563826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16595
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