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PLX4032 Mediated Melanoma Associated Antigen Potentiation in Patient Derived Primary Melanoma Cells

Over expression of various immunogenic melanoma associated antigens (MAAs) has been exploited in the development of immunotherapeutic melanoma vaccines. Expression of MAAs such as MART-1 and gp100 is modulated by the MAPK signaling pathway, which is often deregulated in melanoma. The protein BRAF, a...

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Dettagli Bibliografici
Pubblicato in:J Cancer
Autori principali: George, Andrea L., Suriano, Robert, Rajoria, Shilpi, Osso, Maria C., Tuli, Neha, Hanly, Elyse, Geliebter, Jan, Arnold, Angelo N., Wallack, Marc, Tiwari, Raj K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643088/
https://ncbi.nlm.nih.gov/pubmed/26640592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.11126
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