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PLX4032 Mediated Melanoma Associated Antigen Potentiation in Patient Derived Primary Melanoma Cells

Over expression of various immunogenic melanoma associated antigens (MAAs) has been exploited in the development of immunotherapeutic melanoma vaccines. Expression of MAAs such as MART-1 and gp100 is modulated by the MAPK signaling pathway, which is often deregulated in melanoma. The protein BRAF, a...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: George, Andrea L., Suriano, Robert, Rajoria, Shilpi, Osso, Maria C., Tuli, Neha, Hanly, Elyse, Geliebter, Jan, Arnold, Angelo N., Wallack, Marc, Tiwari, Raj K.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643088/
https://ncbi.nlm.nih.gov/pubmed/26640592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.11126
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