Inhibition of microRNA-497 ameliorates anoxia/reoxygenation injury in cardiomyocytes by suppressing cell apoptosis and enhancing autophagy

MiR-497 is predicted to target anti-apoptosis gene Bcl2 and autophagy gene microtubule-associated protein 1 light chain 3 B (LC3B), but the functional consequence of miR-497 in response to anoxia/reoxygenation (AR) or ischemia/reperfusion (IR) remains unknown. This study was designed to investigate...

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Udgivet i:Oncotarget
Main Authors: Li, Xixian, Zeng, Zhi, Li, Qingman, Xu, Qiulin, Xie, Jiahe, Hao, Huixin, Luo, Guangjin, Liao, Wangjun, Bin, Jianping, Huang, Xiaobo, Liao, Yulin
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper: Pathology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643066/
https://ncbi.nlm.nih.gov/pubmed/26299920
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