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Mutational Hotspot of TET2, IDH1, IDH2, SRSF2, SF3B1, KRAS, and NRAS from Human Systemic Mastocytosis Are Not Conserved in Canine Mast Cell Tumors

INTRODUCTION: Both canine cutaneous mast cell tumor (MCT) and human systemic mastocytosis (SM) are characterized by abnormal proliferation and accumulation of mast cells in tissues and, frequently, by the presence of activating mutations in the receptor tyrosine kinase V-Kit Hardy-Zuckerman 4 Feline...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zorzan, Eleonora, Hanssens, Katia, Giantin, Mery, Dacasto, Mauro, Dubreuil, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643045/
https://ncbi.nlm.nih.gov/pubmed/26562302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142450
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