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Early Life Exposure to Fructose Alters Maternal, Fetal and Neonatal Hepatic Gene Expression and Leads to Sex-Dependent Changes in Lipid Metabolism in Rat Offspring

AIM: Fructose consumption is associated with altered hepatic function and metabolic compromise and not surprisingly has become a focus for perinatal studies. We have previously shown that maternal fructose intake results in sex specific changes in fetal, placental and neonatal outcomes. In this foll...

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Udgivet i:PLoS One
Main Authors: Clayton, Zoe E., Vickers, Mark H., Bernal, Angelica, Yap, Cassandra, Sloboda, Deborah M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643022/
https://ncbi.nlm.nih.gov/pubmed/26562417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141962
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