VGF Peptide Profiles in Type 2 Diabetic Patients’ Plasma and in Obese Mice

To address the possible involvement of VGF peptides in obesity and diabetes, we studied type 2 diabetes (T2D) and obese patients, and high-fat diet induced obese mice. Two VGF peptides (NAPP-19 and QQET-30) were identified in human plasma by HPLC-ESI-MS. The VGF C-terminus, the above two cleaved pep...

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Vydáno v:PLoS One
Hlavní autoři: D’Amato, Filomena, Noli, Barbara, Angioni, Laura, Cossu, Efisio, Incani, Michela, Messana, Irene, Manconi, Barbara, Solinas, Paola, Isola, Raffaella, Mariotti, Stefano, Ferri, Gian-Luca, Cocco, Cristina
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643017/
https://ncbi.nlm.nih.gov/pubmed/26562304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142333
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