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Evidence from in vitro replication that O6-methylguanine can adopt multiple conformations.

The effect of O6-methylguanine (m6G) on replication, in a partially double-stranded defined 25-base oligonucleotide, has been studied under nonlimiting conditions of unmodified dNTPs and over an extended time period, using the Klenow fragment of Escherichia coli DNA polymerase I. The sequence surrou...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Dosanjh, M K, Loechler, E L, Singer, B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46430/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8483914/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.3983
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