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Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

The human mutation rate is an essential parameter for studying the evolution of our species, interpreting present-day genetic variation, and understanding the incidence of genetic disease. Nevertheless, our current estimates of the rate are uncertain. Most notably, recent approaches based on countin...

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Publicado en:PLoS Genet
Autores principales: Lipson, Mark, Loh, Po-Ru, Sankararaman, Sriram, Patterson, Nick, Berger, Bonnie, Reich, David
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642934/
https://ncbi.nlm.nih.gov/pubmed/26562831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005550
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