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A polypeptide bound by the chaperonin groEL is localized within a central cavity.

Chaperonins are oligomeric protein complexes that play an essential role in the cell, mediating ATP-dependent polypeptide chain folding in a variety of cellular compartments. They appear to bind early folding intermediates, preventing their aggregation; in the presence of MgATP and a cochaperonin, b...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Braig, K, Simon, M, Furuya, F, Hainfeld, J F, Horwich, A L
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1993
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46429/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8097882/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.3978
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