Renal Transplantation Using Belatacept Without Maintenance Steroids or Calcineurin Inhibitors

Kidney transplantation remains limited by toxicities of calcineurin inhibitors (CNIs) and steroids. Belatacept is a less toxic CNI alternative, but existing regimens rely on steroids and have higher rejection rates. Experimentally, donor bone marrow and sirolimus promote belatacept’s efficacy. To in...

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Pubblicato in:Am J Transplant
Autori principali: Kirk, Allan D., Guasch, Antonio, Xu, He, Cheeseman, Jennifer, Mead, Sue I., Ghali, Ada, Mehta, Aneesh K., Wu, Dona, Gebel, Howard, Bray, Robert, Horan, John, Kean, Leslie S., Larsen, Christian P., Pearson, Thomas C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642731/
https://ncbi.nlm.nih.gov/pubmed/24684552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12712
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