Cytogenetic and genetic pathways in therapy-related acute myeloid leukemia

Therapy-related myelodysplastic syndrome and acute myeloid leukemia (t-MDS/t-AML) are late complications of cytotoxic therapy used in the treatment of malignant diseases. The most common subtype of t-AML (~75% of cases) develops after exposure to alkylating agents, and is characterized by loss or de...

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Bibliographic Details
Published in:Chem Biol Interact
Main Authors: Qian, Zhijian, Joslin, John. M, Tennant, Thelma R., Reshmi, Shalini C., Young, David J., Stoddart, Angela, Larson, Richard A., Le Beau, Michelle M.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642715/
https://ncbi.nlm.nih.gov/pubmed/19958752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2009.11.025
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