Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion

Many Gram-negative bacteria use Type I secretion systems, T1SS, to secrete virulence factors that contain calcium-binding Repeat-in-ToXin (RTX) motifs. Here, we present structural models of an RTX protein, RD, in both its intrinsically disordered calcium-free Apo-state and its folded calcium-bound H...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: O’Brien, Darragh P., Hernandez, Belen, Durand, Dominique, Hourdel, Véronique, Sotomayor-Pérez, Ana-Cristina, Vachette, Patrice, Ghomi, Mahmoud, Chamot-Rooke, Julia, Ladant, Daniel, Brier, Sébastien, Chenal, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642704/
https://ncbi.nlm.nih.gov/pubmed/26374675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14223
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