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Irish setter dogs affected with rod/cone dysplasia contain a nonsense mutation in the rod cGMP phosphodiesterase beta-subunit gene.

Irish setter dogs affected with a rod/cone dysplasia (locus designation, rcd1) display markedly elevated levels of retinal cGMP during postnatal development. The photoreceptor degeneration commences approximately 25 days after birth and culminates at about 1 year when the population of rods and cone...

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Detalhes bibliográficos
Main Authors: Suber, M L, Pittler, S J, Qin, N, Wright, G C, Holcombe, V, Lee, R H, Craft, C M, Lolley, R N, Baehr, W, Hurwitz, R L
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC46427/
https://ncbi.nlm.nih.gov/pubmed/8387203
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