An investigation of causes of false positive single nucleotide polymorphisms using simulated reads from a small eukaryote genome

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) are widely used molecular markers, and their use has increased massively since the inception of Next Generation Sequencing (NGS) technologies, which allow detection of large numbers of SNPs at low cost. However, both NGS data and their analysis are...

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Foilsithe in:BMC Bioinformatics
Main Authors: Ribeiro, Antonio, Golicz, Agnieszka, Hackett, Christine Anne, Milne, Iain, Stephen, Gordon, Marshall, David, Flavell, Andrew J., Bayer, Micha
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642669/
https://ncbi.nlm.nih.gov/pubmed/26558718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0801-z
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