An investigation of causes of false positive single nucleotide polymorphisms using simulated reads from a small eukaryote genome

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) are widely used molecular markers, and their use has increased massively since the inception of Next Generation Sequencing (NGS) technologies, which allow detection of large numbers of SNPs at low cost. However, both NGS data and their analysis are...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Ribeiro, Antonio, Golicz, Agnieszka, Hackett, Christine Anne, Milne, Iain, Stephen, Gordon, Marshall, David, Flavell, Andrew J., Bayer, Micha
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642669/
https://ncbi.nlm.nih.gov/pubmed/26558718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0801-z
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