An investigation of causes of false positive single nucleotide polymorphisms using simulated reads from a small eukaryote genome

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) are widely used molecular markers, and their use has increased massively since the inception of Next Generation Sequencing (NGS) technologies, which allow detection of large numbers of SNPs at low cost. However, both NGS data and their analysis are...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Ribeiro, Antonio, Golicz, Agnieszka, Hackett, Christine Anne, Milne, Iain, Stephen, Gordon, Marshall, David, Flavell, Andrew J., Bayer, Micha
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642669/
https://ncbi.nlm.nih.gov/pubmed/26558718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0801-z
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