Oxacillin sensitization of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius by antisense peptide nucleic acids in vitro

BACKGROUND: Antibiotic resistance genes can be targeted by antisense agents, which can reduce their expression and thus restore cellular susceptibility to existing antibiotics. Antisense inhibitors can be gene and pathogen specific, or designed to inhibit a group of bacteria having conserved sequenc...

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Udgivet i:BMC Microbiol
Main Authors: Goh, Shan, Loeffler, Anette, Lloyd, David H., Nair, Sean P., Good, Liam
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642645/
https://ncbi.nlm.nih.gov/pubmed/26560174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-015-0599-x
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