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X-ray irradiation activates K(+) channels via H(2)O(2) signaling

Ionizing radiation is a universal tool in tumor therapy but may also cause secondary cancers or cell invasiveness. These negative side effects could be causally related to the human-intermediate-conductance Ca(2+)-activated-K(+)-channel (hIK), which is activated by X-ray irradiation and affects cell...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gibhardt, Christine S., Roth, Bastian, Schroeder, Indra, Fuck, Sebastian, Becker, Patrick, Jakob, Burkhard, Fournier, Claudia, Moroni, Anna, Thiel, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642570/
https://ncbi.nlm.nih.gov/pubmed/26350345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13861
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