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One, two or three? Probing the stoichiometry of membrane proteins by single-molecule localization microscopy

Probing the oligomeric state of abundant molecules, such as membrane proteins in intact cells, is essential, but has not been straightforward. We address this challenge with a simple counting strategy that is capable of reporting the oligomeric state of dense, membrane-bound protein complexes. It is...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Fricke, Franziska, Beaudouin, Joel, Eils, Roland, Heilemann, Mike
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642553/
https://ncbi.nlm.nih.gov/pubmed/26358640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14072
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