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TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability

Induced pluripotent stem cells (iPSCs) have revolutionized the world of regenerative medicine; nevertheless, the exact molecular mechanisms underlying their generation and differentiation remain elusive. Here, we investigated the role of the cell fate determinant TRIM32 in modulating such processes....

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Publicat a:Sci Rep
Autors principals: Bahnassawy, Lamia’a, Perumal, Thanneer M., Gonzalez-Cano, Laura, Hillje, Anna-Lena, Taher, Leila, Makalowski, Wojciech, Suzuki, Yutaka, Fuellen, Georg, Sol, Antonio del, Schwamborn, Jens Christian
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642535/
https://ncbi.nlm.nih.gov/pubmed/26307407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13456
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