Early pathogenesis of Duchenne muscular dystrophy modelled in patient-derived human induced pluripotent stem cells

Duchenne muscular dystrophy (DMD) is a progressive and fatal muscle degenerating disease caused by a dystrophin deficiency. Effective suppression of the primary pathology observed in DMD is critical for treatment. Patient-derived human induced pluripotent stem cells (hiPSCs) are a promising tool for...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shoji, Emi, Sakurai, Hidetoshi, Nishino, Tokiko, Nakahata, Tatsutoshi, Heike, Toshio, Awaya, Tomonari, Fujii, Nobuharu, Manabe, Yasuko, Matsuo, Masafumi, Sehara-Fujisawa, Atsuko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642533/
https://ncbi.nlm.nih.gov/pubmed/26290039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12831
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