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NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape

Glioblastoma (grade IV glioma) is the most common and aggressive adult brain tumor. A better understanding of the biology of glioblastoma cells is crucial to identify molecular targets stimulating cell death. NPM1 (nucleophosmin) is a multifunctional chaperone that plays an important role in cancer...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Holmberg Olausson, Karl, Elsir, Tamador, Moazemi Goudarzi, Kaveh, Nistér, Monica, Lindström, Mikael S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642306/
https://ncbi.nlm.nih.gov/pubmed/26559910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16495
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