Plasma 24-metabolite Panel Predicts Preclinical Transition to Clinical Stages of Alzheimer’s Disease

We recently documented plasma lipid dysregulation in preclinical late-onset Alzheimer’s disease (LOAD). A 10 plasma lipid panel, predicted phenoconversion and provided 90% sensitivity and 85% specificity in differentiating an at-risk group from those that would remain cognitively intact. Despite the...

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Bibliografski detalji
Izdano u:Front Neurol
Glavni autori: Fiandaca, Massimo S., Zhong, Xiaogang, Cheema, Amrita K., Orquiza, Michael H., Chidambaram, Swathi, Tan, Ming T., Gresenz, Carole Roan, FitzGerald, Kevin T., Nalls, Mike A., Singleton, Andrew B., Mapstone, Mark, Federoff, Howard J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642213/
https://ncbi.nlm.nih.gov/pubmed/26617567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2015.00237
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