The Causal Role of IL-4 and IL-13 in Schistosoma mansoni Pulmonary Hypertension

Rationale: The etiology of schistosomiasis-associated pulmonary arterial hypertension (PAH), a major cause of PAH worldwide, is poorly understood. Schistosoma mansoni exposure results in prototypical type-2 inflammation. Furthermore, transforming growth factor (TGF)-β signaling is required for exper...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Kumar, Rahul, Mickael, Claudia, Chabon, Jacob, Gebreab, Liya, Rutebemberwa, Alleluiah, Garcia, Alexandra Rodriguez, Koyanagi, Daniel E., Sanders, Linda, Gandjeva, Aneta, Kearns, Mark T., Barthel, Lea, Janssen, William J., Mauad, Thais, Bandeira, Angela, Schmidt, Eric, Tuder, Rubin M., Graham, Brian B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642207/
https://ncbi.nlm.nih.gov/pubmed/26192556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201410-1820OC
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