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Clinical implications of molecular heterogeneity in triple negative breast cancer

Triple negative breast cancer (TNBC) is a molecularly heterogeneous disease lacking recurrent targetable alterations and thus therapeutic advances have been challenging. The absence of ER, PR and HER2 amplifications, leaves combination chemotherapy as the standard of care treatment option in the adj...

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Bibliografiska uppgifter
I publikationen:Breast
Huvudupphovsmän: Lehmann, Brian D., Pietenpol, Jennifer A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641762/
https://ncbi.nlm.nih.gov/pubmed/26253813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.breast.2015.07.009
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