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Clinical implications of molecular heterogeneity in triple negative breast cancer

Triple negative breast cancer (TNBC) is a molecularly heterogeneous disease lacking recurrent targetable alterations and thus therapeutic advances have been challenging. The absence of ER, PR and HER2 amplifications, leaves combination chemotherapy as the standard of care treatment option in the adj...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Breast
Prif Awduron: Lehmann, Brian D., Pietenpol, Jennifer A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641762/
https://ncbi.nlm.nih.gov/pubmed/26253813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.breast.2015.07.009
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