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Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB

According to the neurotrophin deprivation hypothesis, diminished retrograde delivery of neurotrophic support during an early stage of glaucoma pathogenesis is one of the main triggers that induce retinal ganglion cell (RGC) degeneration. Therefore, interfering with neurotrophic signaling seems an at...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dekeyster, Eline, Geeraerts, Emiel, Buyens, Tom, Van den Haute, Chris, Baekelandt, Veerle, De Groef, Lies, Salinas-Navarro, Manuel, Moons, Lieve
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641732/
https://ncbi.nlm.nih.gov/pubmed/26560713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142067
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