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Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB

According to the neurotrophin deprivation hypothesis, diminished retrograde delivery of neurotrophic support during an early stage of glaucoma pathogenesis is one of the main triggers that induce retinal ganglion cell (RGC) degeneration. Therefore, interfering with neurotrophic signaling seems an at...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Dekeyster, Eline, Geeraerts, Emiel, Buyens, Tom, Van den Haute, Chris, Baekelandt, Veerle, De Groef, Lies, Salinas-Navarro, Manuel, Moons, Lieve
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641732/
https://ncbi.nlm.nih.gov/pubmed/26560713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142067
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