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PCR-Based Simple Subgrouping Is Validated for Classification of Gliomas and Defines Negative Prognostic Copy Number Aberrations in IDH Mutant Gliomas

Genetic subgrouping of gliomas has been emphasized recently, particularly after the finding of isocitrate dehydrogenase 1 (IDH1) mutations. In a previous study, we investigated whole-chromosome copy number aberrations (CNAs) of gliomas and have described genetic subgrouping based on CNAs and IDH1 mu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nakae, Shunsuke, Sasaki, Hikaru, Hayashi, Saeko, Hattori, Natsuki, Kumon, Masanobu, Nishiyama, Yuya, Adachi, Kazuhide, Nagahisa, Shinya, Hayashi, Takuro, Inamasu, Joji, Abe, Masato, Hasegawa, Mitsuhiro, Hirose, Yuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641694/
https://ncbi.nlm.nih.gov/pubmed/26558387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142750
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