Trefoil Factor-3 (TFF3) Stimulates De Novo Angiogenesis in Mammary Carcinoma both Directly and Indirectly via IL-8/CXCR2

Mammary carcinoma cells produce pro-angiogenic factors to stimulate angiogenesis and tumor growth. Trefoil factor-3 (TFF3) is an oncogene secreted from mammary carcinoma cells and associated with poor prognosis. Herein, we demonstrate that TFF3 produced in mammary carcinoma cells functions as a prom...

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Veröffentlicht in:PLoS One
Hauptverfasser: Lau, Wai-Hoe, Pandey, Vijay, Kong, Xiangjun, Wang, Xiao-Nan, Wu, ZhengSheng, Zhu, Tao, Lobie, Peter E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641663/
https://ncbi.nlm.nih.gov/pubmed/26559818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141947
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