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Endothelial Nitric Oxide Synthase G894T Polymorphism Associates with Disease Severity in Puumala Hantavirus Infection

INTRODUCTION: Hantavirus infections are characterized by both activation and dysfunction of the endothelial cells. The underlying mechanisms of the disease pathogenesis are not fully understood. Here we tested the hypothesis whether the polymorphisms of endothelial nitric oxide synthase, eNOS G894T,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Koskela, Sirpa, Laine, Outi, Mäkelä, Satu, Pessi, Tanja, Tuomisto, Sari, Huhtala, Heini, Karhunen, Pekka J., Pörsti, Ilkka, Mustonen, Jukka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641644/
https://ncbi.nlm.nih.gov/pubmed/26561052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142872
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