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SAGA and ATAC Histone Acetyl Transferase Complexes Regulate Distinct Sets of Genes and ATAC Defines a Class of p300-Independent Enhancers

Histone acetyltransferase (HAT) complexes are coactivators that are important for transcriptional activation by modifying chromatin. Metazoan SAGA and ATAC are distinct multisubunits complexes that share the same catalytic HAT subunit (GCN5 or PCAF). Here, we show that these human HAT complexes are...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Krebs, Arnaud R., Karmodiya, Krishanpal, Lindahl-Allen, Marianne, Struhl, Kevin, Tora, Làszlò
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641564/
https://ncbi.nlm.nih.gov/pubmed/22055187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.08.037
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