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Interaction between phosphodiesterases in the regulation of the cardiac β-adrenergic pathway

In cardiac myocytes, the second messenger cAMP is synthesized within the β-adrenergic signaling pathway upon sympathetic activation. It activates Protein Kinase A (PKA) mediated phosphorylation of multiple target proteins that are functionally critical to cardiac contractility. The dynamics of cAMP...

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Bibliografiset tiedot
Julkaisussa:J Mol Cell Cardiol
Päätekijät: Zhao, Claire Y., Greenstein, Joseph L., Winslow, Raimond L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641241/
https://ncbi.nlm.nih.gov/pubmed/26388264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.09.011
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