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Mutant p53: Multiple Mechanisms Define Biologic Activity in Cancer

The functional importance of p53 as a tumor suppressor gene is evident through its pervasiveness in cancer biology. The p53 gene is the most commonly altered gene in human cancer; however, not all genetic alterations are biologically equivalent. The majority of alterations involve p53 missense mutat...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Oncol
Prif Awduron: Kim, Michael Paul, Zhang, Yun, Lozano, Guillermina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641161/
https://ncbi.nlm.nih.gov/pubmed/26618142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00249
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