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Oncogenic role of p21 in hepatocarcinogenesis suggests a new treatment strategy

A well-known tumor suppressor, p21, acts paradoxically by promoting tumor growth in some cellular conditions. These conflicting functions have been demonstrated in association with the HBx gene and in hepatocarcinogenesis. The molecular behavior of p21 depends on its subcellular localization. Nuclea...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Ohkoshi, Shogo, Yano, Masahiko, Matsuda, Yasunobu
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641132/
https://ncbi.nlm.nih.gov/pubmed/26576099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i42.12150
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