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Single-cell systems level analysis of human Toll-Like-Receptor activation defines a chemokine signature in Systemic Lupus Erythematosus

BACKGROUND: Activation of Toll-Like Receptors (TLRs) induces inflammatory responses involved in immunity to pathogens and autoimmune pathogenesis, such as in Systemic Lupus Erythematosus (SLE). Although TLRs are differentially expressed across the immune system, a comprehensive analysis of how multi...

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Bibliografiska uppgifter
I publikationen:J Allergy Clin Immunol
Huvudupphovsmän: O'Gorman, William E., Hsieh, Elena W.Y., Savig, Erica S., Gherardini, Pier Federico, Hernandez, Joseph D., Hansmann, Leo, Balboni, Imelda M., Utz, Paul J., Bendall, Sean C., Fantl, Wendy J., Lewis, David B., Nolan, Garry P., Davis, Mark M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640970/
https://ncbi.nlm.nih.gov/pubmed/26037552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.04.008
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