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Defective cancellous bone structure and abnormal response to PTH in cortical bone of mice lacking Cx43 cytoplasmic C-terminus domain

Connexin43 (Cx43) forms gap junction channels and hemichannels that allow the communication among osteocytes, osteoblasts, and osteoclasts. Cx43 carboxy-terminal (CT) domain regulates channel opening and intracellular signaling by acting as a scaffold for structural and signaling proteins. To determ...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Pacheco-Costa, Rafael, Davis, Hannah M., Sorenson, Chad, Hon, Mary C., Hassan, Iraj, Reginato, Rejane D., Allen, Matthew R., Bellido, Teresita, Plotkin, Lilian I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640960/
https://ncbi.nlm.nih.gov/pubmed/26409319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.09.011
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