The Retinoblastoma Tumor Suppressor Transcriptionally Represses Pak1 in Osteoblasts

We previously characterized the retinoblastoma tumor suppressor protein (Rb) as a regulator of adherens junction assembly and cell-to-cell adhesion in osteoblasts. This is a novel function since Rb is predominantly known as a cell cycle repressor. Herein, we characterized the molecular mechanisms by...

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Pubblicato in:PLoS One
Autori principali: Sosa-García, Bernadette, Vázquez-Rivera, Viviana, González-Flores, Jonathan N., Engel, Brienne E., Cress, W. Douglas, Santiago-Cardona, Pedro G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640669/
https://ncbi.nlm.nih.gov/pubmed/26555075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142406
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