Retinoic Acid Ameliorates Pancreatic Fibrosis and Inhibits the Activation of Pancreatic Stellate Cells in Mice with Experimental Chronic Pancreatitis via Suppressing the Wnt/β-Catenin Signaling Pathway

Pancreatic fibrosis, a prominent feature of chronic pancreatitis (CP), induces persistent and permanent damage in the pancreas. Pancreatic stellate cells (PSCs) provide a major source of extracellular matrix (ECM) deposition during pancreatic injury, and persistent activation of PSCs plays a vital r...

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Udgivet i:PLoS One
Main Authors: Xiao, Wenqin, Jiang, Weiliang, Shen, Jie, Yin, Guojian, Fan, Yuting, Wu, Deqing, Qiu, Lei, Yu, Ge, Xing, Miao, Hu, Guoyong, Wang, Xingpeng, Wan, Rong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640570/
https://ncbi.nlm.nih.gov/pubmed/26556479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141462
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