Triptolide Inhibited Cytotoxicity of Differentiated PC12 Cells Induced by Amyloid-Beta(25–35) via the Autophagy Pathway

Evidence shows that an abnormal deposition of amyloid beta-peptide(25–35) (Aβ(25–35)) was the primary cause of the pathogenesis of Alzheimer’s disease (AD). And the elimination of Aβ(25–35) is considered an important target for the treatment of AD. Triptolide (TP), isolated from Tripterygium wilford...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Xu, Pengjuan, Li, Zhigui, Wang, Hui, Zhang, Xiaochen, Yang, Zhuo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640509/
https://ncbi.nlm.nih.gov/pubmed/26554937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142719
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