New Insights into the Pathogenesis of IgA Nephropathy

BACKGROUND: IgA nephropathy, a frequent cause of end-stage renal disease, is an autoimmune disease wherein immune complexes consisting of IgA1 with galactose-deficient O-glycans (autoantigen) and anti-glycan autoantibodies deposit in glomeruli and induce renal injury. Multiple genetic loci associate...

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Detalhes bibliográficos
Publicado no:Kidney Dis (Basel)
Main Authors: Novak, Jan, Rizk, Dana, Takahashi, Kazuo, Zhang, XianWen, Bian, Qi, Ueda, Hiroyuki, Ueda, Yoshimi, Reily, Colin, Lai, Ling-Yun, Hao, Chuanming, Novak, Lea, Huang, Zhi-Qiang, Renfrow, Matthew B., Suzuki, Hitoshi, Julian, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2015
Assuntos:
IgA Nephropathy: Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640461/
https://ncbi.nlm.nih.gov/pubmed/26568951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000382134
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