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Inhibition of histone methyltransferases SUV39H1 and G9a leads to neuroprotection in an in vitro model of cerebral ischemia

Cerebral ischemia induces a complex transcriptional response with global changes in gene expression. It is essentially regulated by transcription factors as well as epigenetic players. While it is well known that the inhibition of transcriptionally repressive histone deacetylases leads to neuroprote...

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Detalles Bibliográficos
Publicado en:J Cereb Blood Flow Metab
Main Authors: Schweizer, Sophie, Harms, Christoph, Lerch, Heike, Flynn, Jennifer, Hecht, Jochen, Yildirim, Ferah, Meisel, Andreas, Märschenz, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640311/
https://ncbi.nlm.nih.gov/pubmed/25966950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.99
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