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S-nitrosated polypropylene sulfide nanoparticles for thiol-dependent transnitrosation and toxicity against adult female filarial worms

A synthetic polymer nanoparticle formulation utilizing the physiological nitrosothiol chemistry for nitric oxide delivery. Toxicity of SNO-NP against adult female Brugia malayi worms, which are responsible for lymphatic filariasis, is dependent on nitric oxide release through transnitrosation as S-n...

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Detalhes bibliográficos
Publicado no:Adv Healthc Mater
Main Authors: Schudel, Alex, Kassis, Timothy, Dixon, J. Brandon, Thomas, Susan N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640194/
https://ncbi.nlm.nih.gov/pubmed/25939735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400841
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