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Inferring intra-motif dependencies of DNA binding sites from ChIP-seq data

BACKGROUND: Statistical modeling of transcription factor binding sites is one of the classical fields in bioinformatics. The position weight matrix (PWM) model, which assumes statistical independence among all nucleotides in a binding site, used to be the standard model for this task for more than t...

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Publié dans:BMC Bioinformatics
Auteurs principaux: Eggeling, Ralf, Roos, Teemu, Myllymäki, Petri, Grosse, Ivo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640111/
https://ncbi.nlm.nih.gov/pubmed/26552868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0797-4
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